Brand Name: Glutamed Active ingredients: Glutamed (a complex of copper (II) with glutamic acid) and potassium iodide Release form: Tablets, in blisters and in bottles Composition: 1 tablet contains active substances: light blue tablet – glutamed – 0.002 g. white tablet – potassium iodide – 131 mkg (dose equivalent to 100 mkg elemental iodine) Excipients: Sugar, starch, calcium stearate Pharmacotherapeutic group: Means for the treatment of endocrine system pathology
Pharmacological properties
The drug due to the content in its composition of two different bioactive substances has a wide range of pharmacological properties.
The most important role of iodine in the human body is its participation in the process of hormonogenesis occurring in the thyroid gland. Iodine ions entering the thyroid follicle epithelial cells from potassium iodide tablets under the influence of the enzyme iodide peroxidase are oxidized to elemental iodine, which is incorporated into the tyrosine molecule. In this case, one part of the tyrosine radicals in thyroglobulin is iodinated, resulting in the formation of thyronins, the main of which are thyroxine and triiodothyronine. Thyronins form a complex with thyroglobulin protein, which is deposited in the colloid of the thyroid follicle.
Indications for use
It is used for the treatment of iodine deficiency diseases, including hypothyroidism: with hypothyroidism, subclinical and manifest stages of hypothyroidism, diffuse goiter, diffuse goiter with an autoimmune component, mixed goiter, nodular / multinodal colloid proliferating goiter, thyroid thyroiditis, and hypothyroidism.